Facial pose estimation has gained a lot of attentions in many practical applications, such as human-robot interaction, gaze estimation and driver monitoring. Meanwhile, end-to-end deep learning-based facial pose estimation is becoming more and more popular. However, facial pose estimation suffers from a key challenge: the lack of sufficient training data for many poses, especially for large poses. Inspired by the observation that the faces under close poses look similar, we reformulate the facial pose estimation as a label distribution learning problem, considering each face image as an example associated with a Gaussian label distribution rather than a single label, and construct a convolutional neural network which is trained with a multi-loss function on AFLW dataset and 300W-LP dataset to predict the facial poses directly from color image. Extensive experiments are conducted on several popular benchmarks, including AFLW2000, BIWI, AFLW and AFW, where our approach shows a significant advantage over other state-of-the-art methods.