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LLM Failure Modes in Medical QA Arising from Inflexible Reasoning (arxiv.org)
3 points by docere on Feb 10, 2025 | hide | past | pdf | discuss on HN

In plain words: A set of clinical scenarios is built to trigger the Einstellung effect—fixation on a familiar pattern—to test whether AI models copy patterns instead of reasoning flexibly. The models scored well below doctors, often hallucinating and staying overconfident in wrong answers.

Abstract · Limitations of Large Language Models in Clinical Problem-Solving Arising from Inflexible Reasoning

Large Language Models (LLMs) have attained human-level accuracy on medical question-answer (QA) benchmarks. However, their limitations in navigating open-ended clinical scenarios have recently been shown, raising concerns about the robustness and generalizability of LLM reasoning across diverse, real-world medical tasks. To probe potential LLM failure modes in clinical problem-solving, we present the medical abstraction and reasoning corpus (M-ARC). M-ARC assesses clinical reasoning through scenarios designed to exploit the Einstellung effect -- the fixation of thought arising from prior experience, targeting LLM inductive biases toward inflexible pattern matching from their training data rather than engaging in flexible reasoning. We find that LLMs, including current state-of-the-art o1 and Gemini models, perform poorly compared to physicians on M-ARC, often demonstrating lack of commonsense medical reasoning and a propensity to hallucinate. In addition, uncertainty estimation analyses indicate that LLMs exhibit overconfidence in their answers, despite their limited accuracy. The failure modes revealed by M-ARC in LLM medical reasoning underscore the need to exercise caution when deploying these models in clinical settings.

Jonathan Kim, Anna Podlasek, Kie Shidara, Feng Liu, Ahmed Alaa, Danilo Bernardo
arXiv:2502.04381 · cs.CL, cs.AI · submitted Feb 5, 2025
abstract · pdf · html · 14 pages, 6 figures

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