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Agentic AI for Scientific Discovery: Progress, Challenges, and Future Directions (arxiv.org)
1 point by ceolin on Sep 17, 2025 | hide | past | pdf | discuss on HN

In plain words: AI assistants that can reason, plan, and act on their own are being used to search papers, suggest hypotheses, run experiments, and analyze results. This survey sorts these systems across chemistry, biology, and materials science, finding that reliability, ethics, and keeping humans involved remain the main unsolved problems.

Abstract · Agentic AI for Scientific Discovery: A Survey of Progress, Challenges, and Future Directions

The integration of Agentic AI into scientific discovery marks a new frontier in research automation. These AI systems, capable of reasoning, planning, and autonomous decision-making, are transforming how scientists perform literature review, generate hypotheses, conduct experiments, and analyze results. This survey provides a comprehensive overview of Agentic AI for scientific discovery, categorizing existing systems and tools, and highlighting recent progress across fields such as chemistry, biology, and materials science. We discuss key evaluation metrics, implementation frameworks, and commonly used datasets to offer a detailed understanding of the current state of the field. Finally, we address critical challenges, such as literature review automation, system reliability, and ethical concerns, while outlining future research directions that emphasize human-AI collaboration and enhanced system calibration.

Mourad Gridach, Jay Nanavati, Khaldoun Zine El Abidine, Lenon Mendes, Christina Mack
arXiv:2503.08979 · cs.CL · submitted Mar 12, 2025
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